Anastasios Tzingounis

Anastasios Tzingounis is a Professor in the Department of Physiology and Neurobiology at the University of Connecticut. He holds a Ph.D. from the Vollum Institute at Oregon Health & Sciences University. His research focuses on molecular and cellular mechanisms underlying epileptogenesis, particularly the role of epilepsy-associated genes and potassium channels in neuronal excitability. Key projects include studying KCNQ2/3 channels in interneurons, their impact on cortical excitatory/inhibitory balance, and their implications in epilepsy syndromes.

Research interests emphasize genetic epilepsies, KCNQ channel function, and respiratory defects linked to epilepsy. Collaborations include work with Dr. LoTurco (in vivo neuronal activity imaging) and Dr. Mulkey (respiratory physiology studies). His Tzingounis Lab employs electrophysiology, microscopy, and genetically modified mice to investigate these pathways.

Recent studies explore KCNQ channel mutations, their effects on neuronal populations, and potential anticonvulsant therapies. His work bridges basic science and clinical applications, aiming to develop targeted treatments for neurodevelopmental disorders. No awards are explicitly listed, but his contributions are reflected in high-impact publications and collaborative projects.

Advising and grants: No specific grants or student advisees listed here, but the lab actively recruits graduate students. The lab's future directions include expanding studies on non-ion channel epilepsy genes and SUDEP mechanisms.