Anabel-Lise Le Roux

Anabel-Lise Le Roux is a Researcher at the Institute for Bioengineering of Catalonia (IBEC) within the Cellular and Molecular Mechanobiology research group. Her work focuses on understanding how mechanical forces and membrane dynamics regulate cellular processes, particularly in the context of signaling pathways, mechanotransduction, and cancer biology. She employs advanced imaging and biophysical techniques to study protein-membrane interactions and their implications in health and disease.

Key research themes include lipid-driven protein self-assembly (e.g., Src kinase), membrane curvature sensing by BAR proteins, and the role of mechanical strain in secretory trafficking. Her findings bridge biophysics and cell biology, with applications in understanding cellular mechanosensing and oncogenic transformation mechanisms. Collaborations span experimental and theoretical approaches, including computational modeling of protein-membrane interactions.

Le Roux’s contributions include pioneering studies on YAP nuclear entry mechanics and membrane tension regulation at the leading edge of migrating cells. Her work has been published in high-impact journals such as *Nature Communications*, *Elife*, and *The EMBO Journal*.