
About
Ana Fiszbein is an Assistant Professor of Biology at Boston University, specializing in gene regulation and RNA processing. Her lab employs high-throughput genomics, bioinformatics, and molecular approaches to study co-transcriptional gene regulation in mammalian systems, with a focus on cancer genomics and therapeutic strategies. She earned her PhD from the University of Buenos Aires and leads research on how gene architecture influences transcriptional programs.
Her research interests include understanding the interplay between transcription and splicing, particularly through phenomena like Exon-Mediated Activation of Transcription Starts (EMATS). The lab develops computational tools like evopython to predict gene regulatory networks and designs strategies to manipulate gene expression for therapeutic applications.
Current projects explore promoter-driven RNA processing decisions, transcriptional interference between promoters, and the connection between transcript initiation and termination. The lab actively recruits undergraduate, graduate, and postdoctoral researchers. Key findings include the discovery of hybrid exons and splicing-dependent transcriptional control mechanisms.
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