
Amy E. Keating
Professor · Protein Interaction Design
Massachusetts Institute of TechnologyAbout
Amy E. Keating is the Jay A. Stein (1968) Professor of Biology and Professor of Biological Engineering at MIT, serving as Department Head of Biology. She holds a PhD (1998) from UCLA in Physics and an SB (1992) in Physics from Harvard University. Her research focuses on understanding protein interaction mechanisms and designing synthetic protein interactions, with expertise in α-helical coiled-coils, Bcl-2 proteins, and short linear motif interactions.
Recent work includes studies on STAT5B mutations in leukemia, high-throughput protein fragment discovery using AlphaFold, and structural analysis of EVH1 domains. Her lab employs integrative approaches combining computational modeling, bioinformatics, and biochemical experiments.
No scientific awards explicitly listed, though her work suggests significant contributions to protein engineering. Advising details are not provided in the text. She leads a lab at the Koch Biology Building, collaborating on projects involving protein design and disease mechanisms.
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