Amit Meller

Prof. Amit Meller is a Full Professor of Biomedical Engineering at Technion-Israel Institute of Technology and holds adjunct roles at Boston University (Adjunct Associate Professor in Biomedical Engineering and Materials Science & Engineering). He earned his Ph.D. in Physics and Biophysics from the Weizmann Institute of Science, followed by M.Sc. and B.Sc. degrees in Physics from Weizmann and Tel Aviv University, respectively.

Research Interests: Dr. Meller’s work focuses on developing novel experimental techniques for studying biomolecular interactions at the single-molecule level. Key areas include nanopore force spectroscopy for RNA/DNA analysis, ultra-fast DNA sequencing, and single-molecule optical methods. His lab pioneered silicon-based nanofluidic devices for high-resolution protein separation and developed nanoscale biosensors for precision medicine applications. Recent advancements include amplification-free mitochondrial DNA quantification and sub-micrometer channel-based SDS-PAGE for clinical diagnostics.

Lab & Collaborations: The Meller Lab at Technion employs interdisciplinary approaches, combining nanotechnology, optics, and machine learning. Collaborations include work with Prof. Oded Lewinson on bacterial transporter dynamics and the development of parallel STED microscopy for live-cell imaging. Recent projects involve optoelectronic nanopore control and machine learning-based protein identification.

News Highlights:

• 2025: Presented research at the CECAM workshop in Italy and published a review on nanofluidics in Analytical Chemistry.
• 2025: Published in ACS Nano on ultra-long genomic DNA manipulation and developed machine learning tools for cfDNA analysis.
• 2022-2024: Advanced nanopore-based protein sensing, surfactant-enhanced DNA translocation, and light-enhanced biosensors.

Advising & Training: Mentored students like Noam (PhD graduate), Malak Hijazi (studying cfDNA fragmentation), and Jiban Mondal (recent lab joiner). Focus on training in nanopore technology, single-molecule imaging, and bio-nano device fabrication.