Alpaslan Tasdogan

Prof. Dr. Dr. Alpaslan Tasdogan serves as a Research Group Leader in the Department of Translational Research at the Leibniz Institute for Analytical Sciences (ISAS) in Dortmund, Germany. He heads the Preclinical Metabolomics research group, focusing on advanced metabolomic applications in disease research.

His research centers on metabolic dysregulation in cancer, integrating metabolomics with molecular biology to elucidate mechanisms of tumor progression. Key interests include:

• Preclinical metabolomics profiling
• Amino acid signaling pathways (particularly aspartate) in metastasis
• Alternative protein translation in cancer cells
• Translational applications for cancer diagnostics
• Metabolic drivers of lung cancer metastasis

His recent Nature (2025) publication demonstrates how aspartate signaling promotes lung metastasis through alternative translation mechanisms, highlighting novel metabolic vulnerabilities in cancer. This work bridges fundamental metabolomics with therapeutic development.

No scientific awards or student advising information was documented in the provided materials. Research is conducted through the Preclinical Metabolomics group within ISAS's Translational Research department, utilizing the institute's analytical infrastructure at the Dortmund campus.