Alexis GRANDE

Alexis GRANDE is an Associate Professor at the University of Modena and Reggio Emilia, affiliated with the Department of Biomedical, Metabolic and Neuroscience Sciences. His research focuses on cell biology, oncology, epigenetics, bone biology, and molecular mechanisms in cancer and inflammation. He teaches courses in Biologia e Genetica for medical and dental programs.

Research Interests:

• Osteoclast differentiation and bisphosphonate-induced osteonecrosis of the jaw (ONJ)
• Epigenetic regulation in acute myeloid leukemia (AML) and colorectal cancer (CRC)
• Role of cadherins and microRNAs in cancer progression
• β-catenin signaling in colorectal carcinogenesis
• Vitamin D and magnesium’s roles in cell differentiation and therapy

Recent Articles: Recent work highlights magnesium’s enhancement of osteoclast differentiation, PEMF effects on bone healing, and epigenetic targeting in AML. Key themes include bone biology, cancer epigenetics, and therapeutic mechanisms.

Grants & Awards: No awards explicitly mentioned, but active in grant-funded research areas such as leukemia differentiation and bone biology.

Advising & Labs: Advises on molecular mechanisms of disease and collaborates on projects involving cell differentiation and oncology. No specific lab mentioned, but affiliated with the department’s research groups.