Alexandre Persat

Alexandre Persat is an Associate Professor at the École Polytechnique Fédérale de Lausanne (EPFL) within the School of Engineering (SV). He holds academic roles in multiple departments, including the Department of Life Sciences Engineering and leads the Persat Lab (UPPERSAT). His research focuses on microbiology, mechanobiology, and biophysics, with a particular emphasis on protein aggregation and neurodegenerative diseases like Parkinson's.

Education details are not explicitly provided, but his professional roles indicate advanced academic training in life sciences. His work bridges molecular mechanisms of protein misfolding and their cellular consequences, with implications for disease modeling and therapeutic development.

Research interests include the mechanical interactions between bacteria and surfaces, biofilm formation, and the role of biomechanical forces in pathogenesis. Key awards include the Egon Naef Prize (2024) and the Philanthropia Foundation Prize (2025), recognizing his contributions to biophysical research.

Persat supervises over 10 doctoral students, including Tania Distler and Alice Cont, and has authored influential papers on α-synuclein aggregation and O-GlcNAc modification effects. His lab (UPPERSAT) explores interdisciplinary approaches to understand mechanobiological processes in both microbial and neuronal contexts.