Alexander Timoshenko

Alexander Timoshenko is an Associate Professor in the Department of Biology at Western University. His research focuses on the cell and molecular biology of galectins, a family of β-galactoside-binding proteins, and their roles in cellular stress responses, differentiation, and cancer biology. He leads a lab investigating glycobiology mechanisms, particularly the interplay between galectins and O-GlcNAc modifications under stress conditions.

Research Interests:
His work explores galectin functions in immune response modulation, cancer progression, and differentiation pathways. Key areas include galectin regulation during neutrophilic differentiation of HL-60 cells, O-GlcNAc-dependent mechanisms, and the role of galectins in lymphangiogenesis and metastasis.

Publications:
Recent work includes studies on galectin-12 secretion, cAMP regulation of LGALS16, and O-GlcNAc modulation in cancer and differentiation contexts. His research spans glycobiology, immunology, and developmental biology.

Teaching:
He teaches courses in cell biology (Biology 3326F/G), molecular cell stress (Biology 3355A), and oversees honors research projects (Biology 4999E). His pedagogical approach emphasizes hands-on laboratory skills and critical analysis of primary literature.

Lab Members & Students:
Current and former students include Rada Tazhitdinova, Sara Christiano, and Jennifer Kaminker. The lab collaborates on projects involving galectin expression profiling and stress-induced cellular changes.