Alexander SKUPIN

Alexander SKUPIN is an Associate Professor and Chief Scientist in the Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg, specializing in Modelling of Biomedical Data. His research focuses on computational systems biology, neurodegenerative diseases, and integrative multi-omics analysis.

Key research interests include modeling cellular energy metabolism, microglial dynamics in neurodegeneration, and calcium signaling dysfunction in Parkinson’s and Alzheimer’s diseases. His work combines experimental data with advanced computational methods to dissect disease mechanisms and predict therapeutic targets.

Recent publications highlight innovations in:

• Sex-specific transcriptomic changes in tauopathy models
• Computational models of astrocytic morphology and mitochondrial efficiency
• Multi-omics integration for Parkinson’s disease intervention points
• Epidemiological modeling using Kalman-filtered SIRS networks

No scientific awards explicitly mentioned.

Advising and grants: No specific advisees or grant details listed, but his work implies leadership in collaborative projects involving organoid models and patient-derived xenografts.

Labs/Teams: Part of LCSB’s Integrative Cell Signalling group, collaborating on systems biomedicine initiatives involving computational modeling and experimental validation.