About
Dr. Alexander Kulminski is an Associate Research Professor at Duke University specializing in the genetics and molecular mechanisms of Alzheimer's disease, aging, and age-related phenotypes. His research focuses on gene-environment interactions, biomarker discovery, and pleiotropy in neurodegenerative disorders.
- Email: kulminsk@duke.edu
- Institution: Duke University
Key research areas include:
- Genetic architecture of Alzheimer's disease risk
- Sex-specific disparities in neurodegeneration
- Physiological dysregulation and resilience markers
- Longitudinal omics data modeling
- Genomic pleiotropy across age-related diseases
His recent publications (2023-2025) demonstrate expertise in analyzing APOE-TOMM40-APOC1 haplotypes, lysophosphatidylcholines, and multi-trait genetic interactions. Methodologies include threshold regression, negative binomial mixed models, and causal mediation analysis with population-based cohorts.
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