Alexander Golovanov
Associate Professor · Structural Biology
The University of ManchesterAbout
Roles & Affiliations: Alexander Golovanov is an Associate Professor (Reader) in the Department of Chemistry, Faculty of Science and Engineering at The University of Manchester. He leads research in structural biology and applications of light-coupled NMR spectroscopy. He coordinates courses BIOL10551 and CHEM10520.
Education:
- MSc equivalent from Moscow Institute of Physics and Technology (1988)
- PhD from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (1994)
Research Interests: Golovanov’s work focuses on protein interactions and their roles in diseases like viral infections and cancer. Key areas include NMR spectroscopy for structural studies, herpesvirus protein ICP27’s role in HSV-1 infection, and methods to prevent protein aggregation in biopharmaceuticals. His lab develops novel NMR techniques for multi-component binding analysis and stabilizes proteins using additives like arginine glutamate.
Research Contributions: Over 91 publications and 2 datasets highlight his work on protein-drug interactions, viral protein dynamics, and formulation stability. His methods have advanced understanding of HSV-1’s molecular mechanisms and improved monoclonal antibody stability.
Grants & Labs: Active in Manchester Institute of Biotechnology. Research aligns with UN Sustainable Development Goals through contributions to healthcare innovation and pharmaceutical advancements.
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