Alex Kleinpeter

Alex Kleinpeter is an Assistant Professor in the Department of Microbiology and Immunology at the University of Iowa, researching HIV-1 replication mechanisms with emphasis on capsid assembly and antiretroviral resistance.

Education:

• BS in Biological Sciences, Louisiana State University
• PhD in Biochemistry and Structural Biology, University of Alabama-Birmingham
• Postdoctoral Fellow, National Cancer Institute (HIV Dynamics and Replication Program)

His lab employs molecular biology, biochemistry, and structural biology to investigate HIV-1 assembly/maturation processes and capsid inhibitor mechanisms, particularly focusing on inositol hexakisphosphate (IP6) roles and resistance pathways for drugs like Lenacapavir.

Recent publications (2019-2025) reveal consistent expertise in HIV structural virology, with dominant themes including IP6-capsid interactions, maturation inhibitor mechanisms, and viral resistance evolution through structural adaptations, often in collaboration with Dr. Eric Freed's NCI laboratory.

Information regarding specific advising activities and grant funding was not provided in source materials. His research laboratory operates from room 3-604 in the Bowen Science Building at the University of Iowa.