Alessandro Bertoli

Alessandro Bertoli serves as Associate Professor in the Department of Biomedical Sciences at the University of Padua, where he has maintained an active research profile since returning in 2002 after postdoctoral work at the Pharmacological Research Institute "Mario Negri" in Milan. His academic foundation includes a Physics degree from the University of Genova (1994) and a PhD in Biochemistry and Biophysics from the University of Padova (2000).

His research trajectory demonstrates deep specialization in neurodegenerative mechanisms, beginning with electrophysiological characterization of CNS and mitochondrial ion channels, evolving through Parkinson's disease and prion protein (PrP) studies, and currently focusing on amyotrophic lateral sclerosis (ALS) pathogenesis. This progression reveals a consistent emphasis on cellular dysregulation pathways, particularly calcium homeostasis failures and mitochondrial-ER network disruptions as central drivers of neurodegeneration across multiple disease contexts.

Prof. Bertoli actively contributes to scholarly discourse as Review Editor for Frontiers in Neuroscience and through journal reviewing activities. His leadership experience includes directing a dedicated research unit at the Mario Negri Institute during his postdoctoral phase, establishing his capacity for independent research direction within neurodegenerative disease frameworks.