Aleksandar Rajkovic

Aleksandar Rajkovic, MD, PhD, serves as Chief Genomics Officer at UCSF Health with a joint academic appointment as a Professor in the Departments of Pathology and Obstetrics, Gynecology and Reproductive Sciences at the University of California San Francisco. He holds the Stuart Lindsay Distinguished Professorship in Experimental Pathology and is affiliated with multiple UCSF campuses including Mission Bay, Parnassus Heights, and Mount Zion.

• BS in Chemistry from Johns Hopkins University (1985)
• MD/PhD in Medicine & Molecular Biology from Case Western Reserve University (1992)
• Residency & Fellowship in Obstetrics/Gynecology and Maternal-Fetal Medicine at Metrohealth Medical Center (1997)
• Medical Genetics Residency at Baylor College of Medicine (1999)

Dr. Rajkovic's research focuses on reproductive genetics and reproductive tract development, particularly investigating genetic causes of human infertility and accelerated reproductive tract aging. His lab discovered critical transcriptional regulators like Nobox, Lhx8, Sohlh1/2, and Hormad1 through animal models and next-generation sequencing of reproductive pathologies.

Current work includes genomic analysis of uterine leiomyomas using Med12 gene variant mouse models and DNA damage response gene studies (MCM8/9) in gonadal dysgenesis. His team applies cutting-edge technologies like single-cell sequencing to understand cellular heterogeneity in reproductive tissues and leverages global genomic databases (gnomAD) for equitable carrier screening frameworks.

Scientific recognition includes:

• Election to Association of American Physicians (2017)
• Keynote Speaker, International Federation of Fertility Societies (2016)
• Stuart Lindsay Distinguished Professorship (2018)
• Multiple research awards from Metrohealth Medical Center and professional societies

His 15 most recent publications (2022-2025) demonstrate expertise in reproductive genomics, covering topics from uterine fibroid pathogenesis and pregnancy loss genetics to pharmacogenomics implementation and diverse population carrier screening. These works employ advanced techniques like optical genome mapping, single-cell sequencing, and cross-institutional electronic health record analysis.