Alejandro Villaverde

Alejandro F. Villaverde is a Ramón y Cajal research fellow in the Department of Systems & Control Engineering at the School of Industrial Engineering, University of Vigo, Spain. He also serves as a Research fellow at CITMAga since 2022. Previously, he worked as a postdoctoral researcher at IIM-CSIC from 2016-2020. His research focuses on the modeling of dynamical systems with particular emphasis on biological applications.

Villaverde earned his PhD in Systems and Control Engineering from University of Vigo between 2005 and 2009. His academic career has centered at Spanish institutions with a strong interdisciplinary approach bridging engineering, mathematics, and biology.

His primary research interests include systems biology, control theory, and mathematical modeling, with specialized expertise in structural identifiability, observability analysis, and computational tools for dynamic modeling of biological systems. Villaverde's work addresses fundamental challenges in building reliable mathematical models of complex biological processes, with applications spanning immunology to microbial communities. His theoretical contributions have practical implications for improving model reliability and predictive power in biological research.

Villaverde has published extensively in top journals including PLOS Computational Biology, Bioinformatics, and IEEE/ACM Transactions on Computational Biology. His recent publications (2023-2025) reveal a consistent research trajectory focused on developing theoretical frameworks for biological model analysis, creating practical software tools, and applying these methods to cutting-edge problems. His work shows particular strength in identifying and addressing fundamental limitations in modeling approaches, especially regarding parameter identifiability and model observability constraints.

• Among the top 2% Scientists Worldwide 2024 (Stanford University list)
• Recognition as one of the EEI's top valued instructors at University of Vigo's School of Industrial Engineering

Villaverde leads multiple significant research projects including DYNAMO-bio (funded by Ministry of Science, Innovation and Universities), SICOMORO (focusing on symmetries in biological communities), and PREDYCTBIO. His group actively develops open-source software tools such as STRIKE-GOLDD for structural identifiability and observability analysis. The laboratory, part of the BICO research group, includes several researchers and students working on various aspects of dynamic modeling in biology, with recent additions including Mahmoud Shams Falavarjani, Adriana González Vázquez, and multiple interns working on specialized projects.