
About
Adrian T. Ting, Ph.D., is a Professor of Immunology in the Department of Immunology at Mayo Clinic College of Medicine, Rochester, Minnesota. He serves as a Senior Associate Consultant II-Research and leads a research laboratory focused on the molecular regulation of cell survival and death pathways, particularly in response to tumor necrosis factor (TNF).
His research spans multiple interconnected areas including immunology, cell signaling, cancer immunotherapy, organ transplantation, and infectious diseases. The core of his work centers on a ubiquitin-dependent checkpoint that controls whether cells survive or undergo RIPK1-mediated death (ripoptocide) in response to TNF. This mechanism has far-reaching implications in disease contexts where immune-mediated killing is either insufficient (e.g., cancer) or excessive (e.g., graft rejection).
Dr. Ting’s work contributes significantly to translational research, particularly through its integration with the Mayo Clinic Comprehensive Cancer Center and the David F. and Margaret T. Grohne Cancer Immunology and Immunotherapeutics Program. Although specific publications are not listed in the provided text, the website indicates a robust record of peer-reviewed research output.
- Immunology Research
- Cancer Immunotherapy
- Translational Mechanisms in Organ Transplantation
- Molecular Regulation of Cell Death
Dr. Ting has received research support through prestigious fellowships, including from the Cancer Research Institute, and his training includes a postdoctoral fellowship at Massachusetts General Hospital under Dr. Brian Seed. His academic journey began with a B.A. in Biology (chemistry minor) from Luther College, followed by doctoral studies in Immunology at Mayo Graduate School.
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